Metabloism of METHOTREXATE

Metabloism of METHOTREXATE

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17675 days ago, 10 views

Pharmacology

Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication. The mechanism involved in its activity against rheumatoid arthritis is not known.

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