What combines research opportunities, intellectual challenge, and international collaboration in the study of a disease which affects many organs of the body and all sectors of society? And demands that specialists from many different backgrounds work together to crack sometimes intractable problems? It is, of course, oncology. As a career choice, it's demanding; it takes passion coupled with a willingness to put in the hours and to learn how to discuss death honestly and sensitively. But for the right person, it can be immensely rewarding.