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The heart makers

2,092 Views • 01/17/24
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samer kareem
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Educational only: videos on MedicalVideos.com are for general information and are not medical advice. Always consult your own doctor about your health.

How do you make a working human heart? Scientists can turn stem cells into beating heart cells, but getting them to organize into a 3D heart requires a scaffold. At the Massachusetts General Hospital in Boston, Harald Ott and his team are reusing the scaffold that nature provides. They’re stripping away all the living cells from dead hearts, before filling in the leftover matrix with healthy new cells. In this video, Brendan Maher finds out how the technique could be used to develop parts of the heart, like the aortic root and valve, for transplant.

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This video presents research on making a working human heart, following work at Massachusetts General Hospital by Harald Ott and his team. It explains that scientists can turn stem cells into beating heart cells but need a scaffold to organize them into a 3D heart, and describes stripping living cells from dead hearts and filling the leftover matrix with healthy new cells, with possible use for parts of the heart such as the aortic root and valve for transplant.

Key points

  • Presents research into making a working human heart
  • Explains stem cells turned into beating heart cells and the need for a scaffold
  • Describes stripping cells from dead hearts to reuse the natural matrix
  • Covers refilling the matrix with healthy new cells
  • Covers possible development of the aortic root and valve for transplant

Video Overview

This video presents “The heart makers” — How do you make a working human heart? Scientists can turn stem cells into beating heart cells, but getting them to organize into a 3D heart requires a scaffold. At the Massachusetts General Hospital in Boston, Harald Ott and his team. Whether you are preparing for a procedure, studying the technique, or learning how a condition is assessed, the recording shows the process as it is performed in practice.

From our Cardiology collection: ECG interpretation, echocardiograms, angioplasty, stents and heart conditions explained by cardiologists. Browse all Cardiology videos →

Educational content only — not a substitute for professional medical advice.

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