What is Major Depressive Disorder?
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Possible causes include a combination of biological, psychological, and social sources of distress. Increasingly, research suggests these factors may cause changes in brain function, including altered activity of certain neural circuits in the brain. The persistent feeling of sadness or loss of interest that characterizes major depression can lead to a range of behavioral and physical symptoms. These may include changes in sleep, appetite, energy level, concentration, daily behavior, or self-esteem. Depression can also be associated with thoughts of suicide. The mainstay of treatment is usually medication, talk therapy, or a combination of the two. Increasingly, research suggests these treatments may normalize brain changes associated with depression.
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This video covers major depressive disorder. It describes possible causes as a combination of biological, psychological and social sources of distress affecting brain function, the persistent sadness or loss of interest and its behavioral and physical symptoms, and that treatment is usually medication, talk therapy, or a combination.
Key points
- Possible causes include biological, psychological and social sources of distress
- These factors may cause changes in brain function and neural circuit activity
- Symptoms can include changes in sleep, appetite, energy, concentration, behavior or self-esteem, and depression can be associated with thoughts of suicide
- Treatment is usually medication, talk therapy, or a combination of the two
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