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Translational Neuroscience of Excessive Daytime Sleepiness (EDS), Fatigue and Hypersomnia.
Translational Neuroscience of Excessive Daytime Sleepiness (EDS), Fatigue and Hypersomnia. Mohammad Torabi Nami 5,393 Views • 2 years ago

M.Torabi Nami MD, PhDc Department of Neuroscience Institute for Cognitive Science Studies (ICSS), Tehran 15948 Iran Torabi_m@iricss.org Abstract Sleepiness, tiredness and fatigue are complaints which must be thoroughly analyzed to eliminate blur and ambiguity. Physiological sleepiness (“sleep pressure”) increases while being awake and additionally underlies the circadian rhythm with a lower threshold to fall asleep during night time. Excessive daytime sleepiness (EDS) is considered normal only after sleep deprivation. Clinically, EDS manifests by frequents daytime napping and/or reduced alertness with automatic behavior or - in its extreme form - in recurrent attacks of sudden, uncontrollable compulsion to sleep also in inappropriate situations (= “sleep attacks”). EDS is “objectively” addressed by measuring the mean sleep latency to four to five nap opportunities throughout the day using the multiple sleep latency test (MSLT) or the maintenance of wakefulness test (MWT). EDS denotes both, a ready entrance into sleep as well as difficulty in staying awake during daytime or accordingly in inappropriate situations. These two partially independent aspects of EDS are separately assessed by the “passive” MSLT and the “active” MWT respectively. For that reason the MSLT and MWT only weakly correlate with each other when tested over a broad range of patients with EDS. It is important to keep in mind, that these tests are importantly influenced by a great variety of factors such as mood, anxiety, and motivation. “Vigilance” comprises wakefulness, alertness and attention and therefore is more than just the reciprocal to sleepiness. Cognitive performance tasks such as Steer Clear Reaction Time Test (SCRTT) or driving simulators require the complete integrity of vigilance to achieve normal results. Hypersomnia is usually broadly defined as the combination of abnormally prolonged night-time sleep (regularly >10 h) with EDS during ≥1 months. On the other hand, the term hypersomnia has also been used in a narrower scene for the isolated abnormality of a prolonged night-time sleep need (>10 h). “Tiredness”, also in colloquial language often used for sleepiness, in a broader sense also describes the feeling of lack of energy, motivation and initiative. These patients seek rest rather than sleep. They often cannot fall asleep when given the opportunity in spite of feeling tired, and hence, in an MSLT, do not show an abnormally short sleep latency. Furthermore, tiredness (and fatigue) as opposed to sleepiness has a mental (“central”) and physiological (bodily or “peripheral”) component, which the patients can readily distinguish. Patients with insomnia, mild sleep apnea syndrome, or depression rather suffer from mental tiredness than sleepiness during the day. The simple subjective self-assessment using the Epworth Sleepiness Scale (ESS) quite reliably differentiates between sleepiness and mental tiredness (without sleepiness), which makes it a widely used test. The term “fatigue” is also heterogeneously used. In physiology the “fatigue” implied a “time on task performance decrement” to describe decreasing muscle force during a sustained physical effort. In clinical medicine one distinguishes physical (“peripheral”) from mental (“central”) fatigue and the term usually denotes a chronic and more abnormal situation than tiredness. In a broad sense “fatigue” implies a deficiency in coping satisfactorily with mental and physical work load. The chronic fatigue syndrome entails both mental as well as a physical fatigue (so called “leaden paralysis” of limbs). Depressive states are often associated with insomnia and fatigue, but there are also cases with hypersomnia rather than insomnia ( non organic hypersomnia , “atypical depression” or “hypersom

Proximal femur & Hip Fixation
Proximal femur & Hip Fixation samer kareem 2,364 Views • 2 years ago

The lateral approach is used for insertion of fixation devices after closed reduction of a proximal femoral fracture. Reduction of a displaced fracture is usually done with a fracture table, or alternatively a large distractor spanning the hip joint. After satisfactory reduction is confirmed by image intensifier, the lateral approach can be used for insertion of a sliding hip screw or multiple screws. The approach provides limited access to the lateral surface of the femur sufficient for hardware placement. The incision can be extended proximally to accommodate a trochanteric stabilizing plate (TSP), or even anteriorly so that it becomes an anterolateral approach with direct, although limited, access to the femoral neck.

Cricotracheal Resection
Cricotracheal Resection samer kareem 20,100 Views • 2 years ago

CTR is a surgery in which the narrowed part of the airway just below the voice box (larynx) is removed and the voice box and windpipe (trachea) are sewn back together. It is also used to treat other airway problems.

Live brain surgery: see how doctors are using A.I. in the O.R.
Live brain surgery: see how doctors are using A.I. in the O.R. Scott 148 Views • 2 years ago

Dr. Akshay Syal takes us to NYU Langone Health where new A.I. technology is diagnosing brain tumors in record time, which opens the doors to possible new life-saving treatments.

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Rectum exam by Proctoscope
Rectum exam by Proctoscope Mohamed 21,339 Views • 2 years ago

Proctoscope rectal examination

Rectal Examinations
Rectal Examinations Scott 21,820 Views • 2 years ago

ectal exam is an internal examination of the rectum such as by a physician or other healthcare professional.
The digital rectal examination (DRE, Latin palpatio per anum or PPA) is a relatively simple procedure. The patient is placed in a position where the anus is accessible and relaxed (lying on the side, squatting on the examination table, bent over the examination table, etc). The physician inserts a gloved and lubricated finger into the rectum through the anus and palpates the insides.
The DRE is inadequate as a screening tool for colorectal cancer because it examines less than 10% of the colorectal mucosa; colonoscopy is preferred. However, it's an important part of a general examination, as many tumors or other diseases are made manifest in the distal part of the rectum.

This examination may be used: * for the diagnosis of rectal tumors and other forms of cancer; * in males, for the diagnosis of prostatic disorders, notably tumors and benign prostatic hyperplasia; * for the diagnosis of appendicitis or other examples of an acute abdomen (i.e. acute abdominal symptoms indicating a serious underlying disease); * for the estimation of the tonicity of the anal sphincter, which may be useful in case of fecal incontinence or neurologic diseases, including traumatic spinal cord injuries; * in females, for gynecological palpations of internal organs * for examination of the hardness and color of the feces (ie. in cases of constipation, and fecal impaction); * prior to a colonoscopy or proctoscopy. * to evaluate haemorrhoids

The DRE is frequently combined with an FOBT (fecal occult blood test), which may be useful for diagnosing the etiology of an anemia and/or confirming a gastrointestinal bleed.

Sometimes proctoscopy may also be part of a rectal examination.

Severe Cystic Acne
Severe Cystic Acne Scott 27,412 Views • 2 years ago

Cystic acne is a severe type of acne in which the pores in the skin become blocked, leading to infection and inflammation. The skin condition mainly affects the face, but also often affects the upper trunk and upper arms. Acne most often affects adolescents and young adults, with an estimated 80 percent of people between 11 and 30 years of age experiencing acne at some point. Cystic acne is the most severe form and affects far fewer people. In 2009, the Centers for Disease Control and Prevention (CDC) found that acne was the top reason people gave for visiting a dermatologist.

Women Health - What is Vaginal Discharge and how to Get Rid of it ?
Women Health - What is Vaginal Discharge and how to Get Rid of it ? hooda 201,637 Views • 2 years ago

Watch that video to know What is Vaginal Discharge and how to Get Rid of it ?

Rectal exam
Rectal exam Surgeon 37,682 Views • 2 years ago

Proctoscopy in Jackknife Position for examination of the rectum

Spleen Palpation
Spleen Palpation M_Nabil 24,471 Views • 2 years ago

Spleen Palpation

Clinical case discussion - Goitre
Clinical case discussion - Goitre Dr.Neelesh Bhandari 32,930 Views • 2 years ago

Clinical case discussion for exams.
Useful for medical students and others.

Tongue Piercing
Tongue Piercing Scott 6,690 Views • 2 years ago

This video demonstrates tongue piercing procedure done OUTSIDE a clinical setting

Male Foley Catheter Insertion Procedure
Male Foley Catheter Insertion Procedure DrHouse 151,543 Views • 2 years ago

Male Foley Catheter Insertion

Natural vaginal child birth delivery video
Natural vaginal child birth delivery video Emery King 7,220,840 Views • 2 years ago

At Hutzel Women's Hospital, Dr. Giancarlo Mari performs breakthrough in-utero surgery to save the lives of high-risk twins developing with a rare "shared" circulatory problem. ~ Detroit Medical Center

Pediatric MRI, Kid-Friendly Service
Pediatric MRI, Kid-Friendly Service Emery King 13,706 Views • 2 years ago

As one of the first pediatric centers in the United States to use a new state-of-the-art MRI machine designed especially for kids, Children's Hospital of Michigan continues to deliver world-class, patient-friendly health care. ~ Detroit Medical Center

Giving a full body Orgasm without touching.
Giving a full body Orgasm without touching. samer kareem 30,062 Views • 2 years ago

In this video I show the steps to give a woman a full body energy orgasm without even touching her.

Blackheads, Whiteheads and Cysts!
Blackheads, Whiteheads and Cysts! samer kareem 6,264 Views • 2 years ago

In this video we give examples of five proven techniques for popping. Viewer discretion is advised as this may not be something that all people want to see. Popping isn't for everyone!

Thyroid Examination
Thyroid Examination Mohamed 23,673 Views • 2 years ago

A video showing clinical examination of the thyroid gland

Femoral Hernia Repair
Femoral Hernia Repair Surgeon 20,697 Views • 2 years ago

Femoral Hernia Repair with Prosthetic PHS repair placed on anterior way

WORLD'S FIRST TRULY ANATOMIC MULTI-ROOTED ZIRCONIA DENTAL IMPLANT SOLUTION
WORLD'S FIRST TRULY ANATOMIC MULTI-ROOTED ZIRCONIA DENTAL IMPLANT SOLUTION implant 14,251 Views • 2 years ago

WORLD'S FIRST TRULY ANATOMIC MULTI-ROOTED ZIRCONIA DENTAL IMPLANT SOLUTION dentistry video

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