Fibrodysplasia ossificans progressiva
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Fibrodysplasia ossificans progressiva (FOP) is a disorder in which muscle tissue and connective tissue such as tendons and ligaments are gradually replaced by bone (ossified), forming bone outside the skeleton (extra-skeletal or heterotopic bone) that constrains movement. This process generally becomes noticeable in early childhood, starting with the neck and shoulders and proceeding down the body and into the limbs. Extra-skeletal bone formation causes progressive loss of mobility as the joints become affected. Inability to fully open the mouth may cause difficulty in speaking and eating. Over time, people with this disorder may experience malnutrition due to their eating problems. They may also have breathing difficulties as a result of extra bone formation around the rib cage that restricts expansion of the lungs.
This video in 30 seconds
This video covers fibrodysplasia ossificans progressiva, a disorder in which muscle tissue and connective tissue such as tendons and ligaments are gradually replaced by bone. The description traces how extra-skeletal bone formation generally becomes noticeable in early childhood and progresses, progressively limiting mobility.
Key points
- Fibrodysplasia ossificans progressiva is explained as muscle and connective tissue being gradually replaced by bone
- Extra-skeletal or heterotopic bone formation outside the skeleton is described
- Progression generally starting in early childhood with the neck and shoulders and proceeding down the body into the limbs is described
- Progressive loss of mobility as joints are affected is covered
- Difficulty speaking and eating from inability to fully open the mouth, malnutrition, and breathing difficulties from bone formation around the rib cage are described
Video Overview
This video presents “Fibrodysplasia ossificans progressiva” — Fibrodysplasia ossificans progressiva (FOP) is a disorder in which muscle tissue and connective tissue such as tendons and ligaments are gradually replaced by bone (ossified), forming bone outside the skeleton (extra-skeletal or. Whether you are preparing for a procedure, studying the technique, or learning how a condition is assessed, the recording shows the process as it is performed in practice.
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