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Hoffmann sign
System: Neurological Signs · All neurological signs
What it is — and how it is elicited
Flicking down the nail of the relaxed middle finger produces a quick flexion of the thumb and index finger.
What a positive finding suggests
Associated with upper motor neuron lesions, especially cervical cord disease, particularly when other reflexes are brisk.
◈ Behind the name
Johann Hoffmann (1857–1919), German neurologist.
Related signs — Neurological Signs
Browse the H section of the A–Z list or return to the Clinical Signs hub.
Please note: This page is an educational reference about clinical examination signs. A clinical sign supports — and never replaces — a full clinical evaluation, examination and appropriate testing. A sign being present does not by itself prove a diagnosis, and an absent sign does not rule one out. If you have symptoms that worry you, see a health professional.