Pathergy

System: Skin & Nail Signs · All skin & nail signs

What it is — and how it is elicited

A needle-prick or minor skin injury develops into an exaggerated pustule, papule or ulcer within a day or two, because the skin over-reacts.

What a positive finding suggests

Associated with Behçet's disease, and also seen in pyoderma gangrenosum and Sweet syndrome.

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Please note: This page is an educational reference about clinical examination signs. A clinical sign supports — and never replaces — a full clinical evaluation, examination and appropriate testing. A sign being present does not by itself prove a diagnosis, and an absent sign does not rule one out. If you have symptoms that worry you, see a health professional.