Pemberton's sign

System: Hormone & Metabolic Signs · All hormone & metabolic signs

What it is — and how it is elicited

Raising both arms overhead for a minute or so makes the face become flushed, dusky and engorged, sometimes with breathlessness and prominent neck veins.

What a positive finding suggests

Associated with a large goitre or mass extending behind the sternum, compressing the veins at the thoracic inlet.

◈ Behind the name

Hugh Spear Pemberton (1890–1956), British physician.

Browse the P section of the A–Z list or return to the Clinical Signs hub.

Please note: This page is an educational reference about clinical examination signs. A clinical sign supports — and never replaces — a full clinical evaluation, examination and appropriate testing. A sign being present does not by itself prove a diagnosis, and an absent sign does not rule one out. If you have symptoms that worry you, see a health professional.