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Uhthoff's phenomenon
System: Neurological Signs · All neurological signs
What it is — and how it is elicited
A temporary worsening of neurological symptoms when body temperature rises, for example after a hot bath or exercise.
What a positive finding suggests
Associated with demyelinating disease, especially multiple sclerosis.
◈ Behind the name
Wilhelm Uhthoff (1853–1927), German ophthalmologist who noticed heat- and exercise-related visual loss in multiple sclerosis.
Related signs — Neurological Signs
Browse the U section of the A–Z list or return to the Clinical Signs hub.
Please note: This page is an educational reference about clinical examination signs. A clinical sign supports — and never replaces — a full clinical evaluation, examination and appropriate testing. A sign being present does not by itself prove a diagnosis, and an absent sign does not rule one out. If you have symptoms that worry you, see a health professional.