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Whipple's triad
System: Hormone & Metabolic Signs · All hormone & metabolic signs
What it is — and how it is elicited
Three findings together: symptoms consistent with low blood sugar, a measured low blood glucose at the time, and relief of the symptoms when glucose is given.
What a positive finding suggests
Associated with true hypoglycaemia disorders, classically an insulin-secreting tumour (insulinoma).
◈ Behind the name
Allen Oldfather Whipple (1881–1963), American surgeon.
Related signs — Hormone & Metabolic Signs
Browse the W section of the A–Z list or return to the Clinical Signs hub.
Please note: This page is an educational reference about clinical examination signs. A clinical sign supports — and never replaces — a full clinical evaluation, examination and appropriate testing. A sign being present does not by itself prove a diagnosis, and an absent sign does not rule one out. If you have symptoms that worry you, see a health professional.