Febuxostat

Pronounced fe-BUX-oh-stat

Brand names: Uloric

Type: Xanthine oxidase inhibitor (gout medicine) · All Other Medicines

What Febuxostat is used for

  • Preventing gout attacks when allopurinol is not suitable
  • Lowering uric acid in gout

◆ Kidney note

No dose change is needed in mild to moderate kidney impairment, which can be useful when allopurinol dosing is difficult.

Common side effects

  • Liver test changes
  • Nausea
  • Joint pain
  • Rash

Important cautions

  • Carries a boxed warning about higher risk of heart-related death compared with allopurinol in people with heart disease — it is reserved for when allopurinol is not suitable
  • Starting it can temporarily trigger gout flares

How it comes

Tablets. This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Febuxostat also appears on Medicines That Can Harm the Liver.

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.