Isotretinoin

Pronounced eye-so-TRET-i-noin

Brand names: Accutane, Claravis

Type: Retinoid (severe acne medicine) · All Other Medicines

What Isotretinoin is used for

• Severe acne not responding to other treatments
• Severe nodular and scarring acne

Common side effects

• Very dry lips and skin
• Dry eyes and nose (nosebleeds)
• Muscle and joint aches
• Raised blood fats
• Sun sensitivity

Important cautions

• Causes severe birth defects — it is dispensed only through a strict safety program (iPLEDGE) with pregnancy testing and two forms of contraception where required
• Blood fats and liver tests are monitored, and mood changes should be reported

How it comes

Capsules. This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Isotretinoin also appears on Medicines That Can Harm the Liver.