Leflunomide

Pronounced le-FLOO-nah-mide

Brand names: Arava

Type: Disease-modifying antirheumatic drug (DMARD) · All Other Medicines

What Leflunomide is used for

  • Rheumatoid arthritis
  • Psoriatic arthritis, on specialist advice

Common side effects

  • Diarrhea
  • Nausea
  • Hair thinning
  • Rash
  • Raised blood pressure

Important cautions

  • Can injure the liver — liver tests are monitored
  • Causes birth defects and stays in the body for up to years after stopping unless a washout procedure is used — pregnancy planning requires that washout

How it comes

Tablets. This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Leflunomide also appears on Medicines That Can Harm the Liver.

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.