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Methadone
Pronounced METH-ah-done
Brand names: Dolophine, Methadose
Type: Opioid pain reliever and addiction treatment · All Pain Relief & Fever Medicines
What Methadone is used for
- Treatment of opioid use disorder (in licensed programs)
- Severe chronic pain, on specialist advice
◆ Kidney note
Cleared mainly through the gut rather than the kidneys, so it is sometimes chosen in advanced kidney disease — still specialist-managed.
Common side effects
- Constipation
- Drowsiness
- Sweating
- Nausea
- Dry mouth
Important cautions
- Stays in the body for a very long time, so overdoses can develop slowly days after a dose change — dosing is specialist-led
- Can affect heart rhythm (QT prolongation), so heart tracing and interaction checks are part of safe use
How it comes
Tablets, liquid. This guide lists forms only — it never lists strengths or doses.
Related medicines — Pain Relief & Fever Medicines
Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.