Nirmatrelvir-ritonavir

Pronounced nir-mah-TREL-veer ri-TON-ah-veer

Brand names: Paxlovid

Type: Antiviral combination (COVID-19) · All Antibiotics & Infection Medicines

What Nirmatrelvir-ritonavir is used for

  • COVID-19 in higher-risk outpatients, started early
  • COVID-19 in higher-risk patients unable to use other first-line options

◆ Kidney note

The dose is lowered when kidney function is moderately reduced, and it is not recommended in severe kidney failure on current labeling.

Common side effects

  • Unpleasant or metallic taste
  • Diarrhea
  • Nausea
  • Muscle aches

Important cautions

  • Interacts with a very large number of medicines, including transplant anti-rejection drugs, some statins, and blood thinners — a complete medication review is essential before starting
  • Must be started within the first days of symptoms to help

How it comes

Tablets. This guide lists forms only — it never lists strengths or doses.

Related medicines — Antibiotics & Infection Medicines

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.