Sacubitril-valsartan

Pronounced sah-KYOO-bi-tril val-SAR-tan

Brand names: Entresto

Type: ARNI (heart failure medicine) · All Heart & Blood Pressure Medicines

What Sacubitril-valsartan is used for

  • Heart failure with reduced pumping function
  • Heart failure with preserved pumping function, in selected patients

◆ Kidney note

Kidney function and potassium are monitored; it is used carefully in kidney disease and is a mainstay for heart failure in many kidney patients.

Common side effects

  • Low blood pressure
  • Dizziness
  • Cough
  • High potassium symptoms

Important cautions

  • Can seriously harm an unborn baby — must not be used in pregnancy
  • Must never be taken together with an ACE inhibitor because of swelling (angioedema) risk

How it comes

Tablets, oral pellets. This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Sacubitril-valsartan also appears on Medicines That Can Harm the Kidneys.

Related medicines — Heart & Blood Pressure Medicines

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.