Estradiol

Abbreviation: E2

Panel: Hormone Tests · All hormones tests

Typical adult reference range

Conventional unitsMale 10–50; Female 30–400 (follicular) pg/mL
SI unitsMale 37–184; Female 110–1,468 (follicular) pmol/L

Ranges vary between laboratories and methods — compare your result with the range printed on your own report.

What a high or low result can mean

High estradiol: high values can be seen in pregnancy, estrogen-producing tumors, and liver disease.

Low estradiol: low values may occur after menopause and in ovarian or pituitary disorders.

These are associations, not a diagnosis: the same result can have several causes, and your clinician interprets it with the rest of your results and history.

Good to know

Female levels vary widely across the menstrual cycle; the range shown is a broad follicular-phase guide.

Please note: Reference ranges vary between laboratories, and between the methods and instruments they use — the range printed on your own report is the one your result should be compared with. A result outside the range is not by itself a diagnosis, and a result inside it does not rule out illness. These pages are an educational summary, not medical advice: always discuss your results with the clinician who ordered them, who can interpret them in the context of your health and history.