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Total Complement Activity
Abbreviation: CH50
Panel: Inflammation & Immune Markers · All inflammation tests
Typical adult reference range
| Conventional units | 41–95 U/mL |
| SI units | 41–95 U/mL |
Ranges vary between laboratories and methods — compare your result with the range printed on your own report.
What a high or low result can mean
High total complement activity: high values can be seen as an acute-phase response.
Low total complement activity: low values may occur in inherited complement deficiency and in conditions with complement consumption, including active lupus.
These are associations, not a diagnosis: the same result can have several causes, and your clinician interprets it with the rest of your results and history.
Good to know
A functional assay of the classical complement pathway; ranges vary by laboratory.
Related tests — Inflammation & Immune Markers
Please note: Reference ranges vary between laboratories, and between the methods and instruments they use — the range printed on your own report is the one your result should be compared with. A result outside the range is not by itself a diagnosis, and a result inside it does not rule out illness. These pages are an educational summary, not medical advice: always discuss your results with the clinician who ordered them, who can interpret them in the context of your health and history.