What Does NPO Mean in Medical Terms?

NPO stands for nil per os. Nothing to eat or drink by mouth.

nil per os

Nothing to eat or drink by mouth.

nothing by mouth (order)

Order to take no food or drink — order.

Where you will see NPO

You will most often see NPO in nursing notes, care plans and handovers, medication orders and prescriptions, operation notes and surgical ward charts.

Example

A medication order might be written with “NPO” as shorthand for nil per os.

Related abbreviations

Browse the full Medical Abbreviations guide — 5,715 entries, searchable A–Z and by specialty.

Educational reference only. This guide is for learning and quick reference. Abbreviations vary between hospitals, countries and specialties, and some are discouraged because they can be misread. Always write and interpret orders using your own institution’s approved abbreviation list, and check anything unclear with the prescriber or your local policy.