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Metabloism of METHOTREXATE
Educational only: videos on MedicalVideos.com are for general information and are not medical advice. Always consult your own doctor about your health.
Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication. The mechanism involved in its activity against rheumatoid arthritis is not known.
This video in 30 seconds
This video covers the metabolism and activity of methotrexate. Its anti-tumor activity is described as resulting from inhibition of folic acid reductase, leading to inhibition of DNA synthesis and cellular replication, while its mechanism against rheumatoid arthritis is stated as not known.
Key points
- Anti-tumor activity results from inhibition of folic acid reductase
- DNA synthesis and cellular replication are inhibited as a result
- The mechanism of activity against rheumatoid arthritis is stated as not known
Video Overview
This video presents “Metabloism of METHOTREXATE” — Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication. The mechanism involved in its activity against rheumatoid arthritis is. Whether you are preparing for a procedure, studying the technique, or learning how a condition is assessed, the recording shows the process as it is performed in practice.
From our Pharmacology collection: How drugs work — mechanisms, side effects and prescribing basics explained clearly for medical and pharmacy students. Browse all Pharmacology videos →
Educational content only — not a substitute for professional medical advice.
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Founded by Dr. Mohamed Ibrahim, MD, PhD — physician-scientist.
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