Azathioprine
Pronounced ay-zah-THY-oh-preen
Brand names: Imuran
Type: Antimetabolite immunosuppressant · All Transplant & Immune Medicines
What Azathioprine is used for
- Preventing organ rejection after kidney transplant
- Rheumatoid arthritis
- Inflammatory bowel disease
- Autoimmune hepatitis and other autoimmune diseases
◆ Kidney note
One of the oldest transplant medicines; dose is guided by blood counts, and its interaction with allopurinol matters greatly in kidney patients with gout.
Common side effects
- Nausea and vomiting
- Low white blood cell counts
- Hair thinning
- Rash
- Liver irritation
Important cautions
- Can severely lower blood counts — a genetic enzyme test (TPMT) and regular blood counts guide safe use
- Combining it with the gout medicine allopurinol can cause life-threatening blood count drops — the combination needs major dose adjustment or avoidance
- Raises infection risk and long-term skin cancer risk
How it comes
Tablets, injection (hospital). This guide lists forms only — it never lists strengths or doses.
Toxicity lists: Azathioprine also appears on Medicines That Can Harm the Liver.
Related medicines — Transplant & Immune Medicines
Condition guides on MedicalVideos.com
Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.