Azathioprine

Pronounced ay-zah-THY-oh-preen

Brand names: Imuran

Type: Antimetabolite immunosuppressant · All Transplant & Immune Medicines

What Azathioprine is used for

  • Preventing organ rejection after kidney transplant
  • Rheumatoid arthritis
  • Inflammatory bowel disease
  • Autoimmune hepatitis and other autoimmune diseases

◆ Kidney note

One of the oldest transplant medicines; dose is guided by blood counts, and its interaction with allopurinol matters greatly in kidney patients with gout.

Common side effects

  • Nausea and vomiting
  • Low white blood cell counts
  • Hair thinning
  • Rash
  • Liver irritation

Important cautions

  • Can severely lower blood counts — a genetic enzyme test (TPMT) and regular blood counts guide safe use
  • Combining it with the gout medicine allopurinol can cause life-threatening blood count drops — the combination needs major dose adjustment or avoidance
  • Raises infection risk and long-term skin cancer risk

How it comes

Tablets, injection (hospital). This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Azathioprine also appears on Medicines That Can Harm the Liver.

Related medicines — Transplant & Immune Medicines

Condition guides on MedicalVideos.com

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.