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Cyclosporine
Pronounced SY-klo-spor-een
Brand names: Neoral, Sandimmune, Gengraf
Type: Calcineurin inhibitor (immunosuppressant) · All Transplant & Immune Medicines
What Cyclosporine is used for
- Preventing organ rejection after transplantation
- Severe rheumatoid arthritis
- Severe psoriasis
- Dry eye disease (eye drops)
◆ Kidney note
Toxic to the kidneys at high levels — the original anti-rejection drug whose careful level monitoring made kidney transplant success routine.
Common side effects
- Gum overgrowth
- Increased hair growth
- Tremor
- Raised blood pressure
- Headache
Important cautions
- Blood levels must be monitored — the range between too little (rejection) and too much (toxicity) is narrow
- Raises the risk of serious infections and, long-term, certain cancers including skin cancer and lymphoma
- Grapefruit and many medicines change its level dramatically; different brands are not freely interchangeable
How it comes
Capsules, liquid, eye drops, injection (hospital). This guide lists forms only — it never lists strengths or doses.
Toxicity lists: Cyclosporine also appears on Medicines That Can Harm the Kidneys.
Related medicines — Transplant & Immune Medicines
Condition guides on MedicalVideos.com
Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.