Carbidopa-levodopa

Pronounced kar-bi-DO-pah lev-o-DO-pah

Brand names: Sinemet

Type: Dopamine replacement (Parkinson medicine) · All Neurology Medicines

What Carbidopa-levodopa is used for

  • Parkinson disease
  • Parkinson-like symptoms from other causes, on specialist advice

Common side effects

  • Nausea
  • Dizziness on standing
  • Involuntary movements (dyskinesia) with long use
  • Vivid dreams or hallucinations
  • Darkened urine or sweat

Important cautions

  • Must not be stopped suddenly — abrupt withdrawal can cause a dangerous fever and rigidity syndrome
  • Over years, each amount may wear off sooner ('wearing-off'), so timing relative to meals and protein is adjusted by the care team

How it comes

Tablets, extended-release tablets and capsules, liquid suspension via pump (specialist), inhalation powder. This guide lists forms only — it never lists strengths or doses.

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.