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Duloxetine
Pronounced doo-LOX-e-teen
Brand names: Cymbalta
Type: SNRI antidepressant · All Mental Health Medicines
What Duloxetine is used for
- Depression
- Generalized anxiety disorder
- Nerve pain from diabetes
- Fibromyalgia
- Chronic muscle and joint pain
◆ Kidney note
Generally avoided when kidney function is severely reduced.
Common side effects
- Nausea
- Dry mouth
- Constipation
- Sexual problems
- Dizziness
Important cautions
- Can injure the liver in rare cases — it is generally avoided in people with significant liver disease or heavy alcohol use
- Stopping suddenly can cause discontinuation symptoms — it is tapered with medical guidance
- Antidepressants carry a warning about increased suicidal thoughts in young people
How it comes
Delayed-release capsules. This guide lists forms only — it never lists strengths or doses.
Toxicity lists: Duloxetine also appears on Medicines That Can Harm the Liver.
Related medicines — Mental Health Medicines
Condition guides on MedicalVideos.com
Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.