Medicines for Type 2 Diabetes

These 32 medicines from the Drug Guide are used in type 2 diabetes. A medicine appearing here does not mean it is right for every person with the condition — your prescriber matches the medicine to you. For videos, articles and guides, visit the Type 2 Diabetes condition hub.

MedicineBrand namesUsed for
AcarbosePrecoseType 2 diabetes; Slowing carbohydrate absorption after meals
AlogliptinNesinaType 2 diabetes; Used alone or combined with other diabetes medicines
CanagliflozinInvokanaType 2 diabetes; Reducing kidney and heart complications in diabetic kidney disease
CaptoprilCapotenHigh blood pressure; Heart failure
DapagliflozinFarxigaType 2 diabetes; Heart failure
DulaglutideTrulicityType 2 diabetes; Reducing heart risk in certain patients with type 2 diabetes
DuloxetineCymbaltaDepression; Generalized anxiety disorder
EmpagliflozinJardianceType 2 diabetes; Heart failure
ExenatideByetta, BydureonType 2 diabetes; Used with other diabetes medicines when targets are not met
GlimepirideAmarylType 2 diabetes; Used alone or combined with other diabetes medicines
GlipizideGlucotrolType 2 diabetes; Used alone or combined with other diabetes medicines
GlyburideDiaBeta, GlynaseType 2 diabetes; Diabetes in pregnancy in selected cases, on specialist advice
Insulin aspartNovoLog, FiaspType 1 diabetes; Type 2 diabetes
Insulin degludecTresibaType 1 diabetes; Type 2 diabetes
Insulin detemirLevemirType 1 diabetes; Type 2 diabetes
Insulin glargineLantus, Basaglar, ToujeoType 1 diabetes; Type 2 diabetes
Insulin isophaneHumulin N, Novolin NType 1 diabetes; Type 2 diabetes
Insulin lisproHumalog, AdmelogType 1 diabetes; Type 2 diabetes
Insulin regularHumulin R, Novolin RType 1 diabetes; Type 2 diabetes
IrbesartanAvaproHigh blood pressure; Kidney protection in type 2 diabetes
LinagliptinTradjentaType 2 diabetes; A DPP-4 option often chosen in chronic kidney disease
LiraglutideVictoza, SaxendaType 2 diabetes; Weight management in obesity
LosartanCozaarHigh blood pressure; Kidney protection in type 2 diabetes
MetforminGlucophage, FortametType 2 diabetes; Prediabetes, in selected patients on clinician advice
MetoclopramideReglanNausea and vomiting; Gastroparesis (slow stomach emptying in diabetes)
PioglitazoneActosType 2 diabetes; Fatty liver disease with diabetes, on specialist advice
PregabalinLyricaNerve pain from diabetes and after shingles; Fibromyalgia
RepaglinidePrandinType 2 diabetes; Targeting blood sugar rises after meals
SaxagliptinOnglyzaType 2 diabetes; Used alone or combined with other diabetes medicines
SemaglutideOzempic, Rybelsus, WegovyType 2 diabetes; Weight management in obesity
SitagliptinJanuviaType 2 diabetes; Used alone or combined with other diabetes medicines
TirzepatideMounjaro, ZepboundType 2 diabetes; Weight management in obesity
Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.