HydrocortisoneOver the counter

Pronounced hy-dro-KOR-ti-sone

Brand names: Cortef, Solu-Cortef

Type: Corticosteroid (steroid) · All Hormone & Endocrine Medicines

What Hydrocortisone is used for

  • Replacing steroids the body cannot make (adrenal insufficiency)
  • Severe allergic reactions and shock (hospital)
  • Skin inflammation (creams)
  • Hemorrhoids (creams and suppositories)

Common side effects

  • Raised blood sugar
  • Fluid retention
  • Stomach upset
  • Skin thinning (with prolonged cream use)

Important cautions

  • People with adrenal insufficiency need extra steroid cover during illness or surgery — this is life-saving and should be planned with the care team
  • Do not stop replacement treatment suddenly

How it comes

Tablets, creams and ointments, injection (hospital). This guide lists forms only — it never lists strengths or doses.

Related medicines — Hormone & Endocrine Medicines

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.