Pancrelipase

Pronounced pan-kree-LY-pase

Brand names: Creon, Zenpep

Type: Pancreatic enzyme replacement · All Digestive (GI) Medicines

What Pancrelipase is used for

  • Replacing digestive enzymes in chronic pancreatitis
  • Replacing enzymes in cystic fibrosis and after pancreas surgery

Common side effects

  • Stomach pain
  • Gas
  • Diarrhea or constipation
  • Nausea

Important cautions

  • Taken with every meal and snack to work — the care team adjusts the amount to meals and symptoms
  • Very high amounts have been linked to colon scarring in cystic fibrosis — do not exceed the prescribed amount

How it comes

Delayed-release capsules. This guide lists forms only — it never lists strengths or doses.

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.