Digestive (GI) Medicines
Medicines for the stomach and gut: acid reducers, anti-nausea medicines, laxatives, anti-diarrhoeal medicines and treatments for inflammatory bowel disease.
This page lists all 35 of them in the guide. Open any medicine for its uses, common side effects, major cautions and kidney note.
| Medicine | Brand names | Used for |
|---|---|---|
| Aluminum hydroxide | Amphojel | Heartburn and acid indigestion; Binding phosphate in chronic kidney disease (limited, specialist-led use) |
| Aprepitant | Emend | Preventing nausea and vomiting from chemotherapy; Preventing nausea after surgery |
| Bisacodyl | Dulcolax | Constipation; Emptying the bowel before colonoscopy or surgery |
| Bismuth subsalicylate | Pepto-Bismol | Diarrhea and traveler's diarrhea; Upset stomach and indigestion |
| Calcium carbonate | Tums | Heartburn and acid indigestion; Calcium supplementation |
| Cimetidine | Tagamet | Heartburn; Stomach and intestinal ulcers |
| Dicyclomine | Bentyl | Irritable bowel syndrome cramps; Intestinal spasm pain |
| Docusate | Colace | Preventing hard, dry stools; Reducing straining after surgery or with hemorrhoids |
| Esomeprazole | Nexium | Acid reflux and heartburn (GERD); Stomach and intestinal ulcers |
| Famotidine | Pepcid | Heartburn and acid indigestion; Acid reflux |
| Lactulose | Constulose, Enulose | Constipation; Reducing ammonia buildup in liver failure (hepatic encephalopathy) |
| Lansoprazole | Prevacid | Acid reflux and heartburn (GERD); Stomach and intestinal ulcers |
| Linaclotide | Linzess | Chronic constipation; Irritable bowel syndrome with constipation |
| Loperamide | Imodium | Diarrhea, including traveler's diarrhea; Reducing output from an ileostomy |
| Lubiprostone | Amitiza | Chronic constipation; Irritable bowel syndrome with constipation in women |
| Magnesium hydroxide | Milk of Magnesia | Constipation; Heartburn and acid indigestion |
| Meclizine | Antivert, Bonine | Motion sickness; Vertigo and dizziness from inner ear problems |
| Mesalamine | Lialda, Pentasa, Asacol | Ulcerative colitis; Crohn disease of the colon (some forms) |
| Metoclopramide | Reglan | Nausea and vomiting; Gastroparesis (slow stomach emptying in diabetes) |
| Misoprostol | Cytotec | Preventing stomach ulcers in people taking NSAIDs; Inducing labor and treating postpartum bleeding (hospital) |
| Omeprazole | Prilosec | Acid reflux and heartburn (GERD); Stomach and intestinal ulcers |
| Ondansetron | Zofran | Nausea and vomiting from chemotherapy, radiation, and surgery; Severe stomach flu and other nausea, on clinician judgment |
| Orlistat | Xenical, Alli | Weight management in obesity; Weight management in overweight patients with risk factors |
| Pancrelipase | Creon, Zenpep | Replacing digestive enzymes in chronic pancreatitis; Replacing enzymes in cystic fibrosis and after pancreas surgery |
| Pantoprazole | Protonix | Acid reflux and heartburn (GERD); Stomach and intestinal ulcers |
| Polyethylene glycol | MiraLAX, GlycoLax | Constipation; Preparing the bowel before colonoscopy (higher-volume preparations) |
| Prochlorperazine | Compazine | Severe nausea and vomiting; Migraine-associated nausea |
| Promethazine | Phenergan | Nausea and vomiting; Motion sickness |
| Psyllium | Metamucil | Constipation; Mild cholesterol lowering as part of diet |
| Rabeprazole | Aciphex | Acid reflux and heartburn (GERD); Stomach and intestinal ulcers |
| Scopolamine | Transderm Scop | Preventing motion sickness; Preventing nausea after surgery |
| Senna | Senokot, Ex-Lax | Constipation; Emptying the bowel before procedures |
| Sucralfate | Carafate | Stomach and intestinal ulcers; Preventing stress ulcers in hospital patients |
| Sulfasalazine | Azulfidine | Ulcerative colitis; Crohn disease |
| Ursodiol | Actigall, Urso | Dissolving certain gallstones; Primary biliary cholangitis (a liver bile duct disease) |
Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.