F43.21 — Adjustment disorder with depressed mood

F43.21

ICD-10 Chapter 5: Mental, Behavioral & Neurodevelopmental — illustrative image — Chapter 5: Mental, behavioral and neurodevelopmental disorders (F01–F99) — illustrative image

What this code means

An adjustment disorder is a strong emotional reaction to a life change or stressor, here mainly with depressed mood.

Also called: adjustment disorder with depressed mood.

When this code is used

Used for adjustment disorder with depressed mood.

Where it sits in ICD-10-CM

Code F43.21 belongs to Chapter 5: Mental, behavioral and neurodevelopmental disorders, which covers codes F01–F99 in the FY2027 ICD-10-CM tabular list. The official description above is copied verbatim from the CDC/NCHS FY2027 code file.

Related symptoms

Insomnia

Frequently asked questions

What is ICD-10-CM code F43.21?

F43.21 is the ICD-10-CM diagnosis code for “Adjustment disorder with depressed mood”. An adjustment disorder is a strong emotional reaction to a life change or stressor, here mainly with depressed mood.

When is code F43.21 used?

Used for adjustment disorder with depressed mood. It belongs to Chapter 5 of ICD-10-CM (Mental, behavioral and neurodevelopmental disorders).

This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.