Alpha-1 Antitrypsin

Abbreviation: AAT

Panel: Liver Function Tests · All liver function tests

Typical adult reference range

Conventional units100–200 mg/dL
SI units20–38 µmol/L

Ranges vary between laboratories and methods — compare your result with the range printed on your own report.

What a high or low result can mean

High alpha-1 antitrypsin: high values can be seen as an acute-phase response to inflammation.

Low alpha-1 antitrypsin: low values may occur in inherited alpha-1 antitrypsin deficiency, which can affect liver and lungs.

These are associations, not a diagnosis: the same result can have several causes, and your clinician interprets it with the rest of your results and history.

Please note: Reference ranges vary between laboratories, and between the methods and instruments they use — the range printed on your own report is the one your result should be compared with. A result outside the range is not by itself a diagnosis, and a result inside it does not rule out illness. These pages are an educational summary, not medical advice: always discuss your results with the clinician who ordered them, who can interpret them in the context of your health and history.