Adrenoleukodystrophy explained.
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X-linked adrenoleukodystrophy is a genetic disorder that occurs primarily in males. It mainly affects the nervous system and the adrenal glands, which are small glands located on top of each kidney. In this disorder, the fatty covering (myelin) that insulates nerves in the brain and spinal cord is prone to deterioration (demyelination), which reduces the ability of the nerves to relay information to the brain. In addition, damage to the outer layer of the adrenal glands (adrenal cortex) causes a shortage of certain hormones (adrenocortical insufficiency). Adrenocortical insufficiency may cause weakness, weight loss, skin changes, vomiting, and coma.
This video in 30 seconds
This video explains X-linked adrenoleukodystrophy, a genetic disorder occurring primarily in males. It describes how the myelin insulating nerves in the brain and spinal cord deteriorates, reducing the nerves' ability to relay information, and how damage to the adrenal cortex causes a shortage of certain hormones with symptoms including weakness, weight loss, skin changes, vomiting and coma.
Key points
- X-linked adrenoleukodystrophy is a genetic disorder occurring primarily in males
- It mainly affects the nervous system and the adrenal glands
- Demyelination reduces the ability of nerves to relay information to the brain
- Damage to the adrenal cortex causes adrenocortical insufficiency
- Adrenocortical insufficiency may cause weakness, weight loss, skin changes, vomiting and coma
Video Overview
This video presents “Adrenoleukodystrophy explained.” — X-linked adrenoleukodystrophy is a genetic disorder that occurs primarily in males. It mainly affects the nervous system and the adrenal glands, which are small glands located on top of each kidney. In this disorder, the fatty covering. Whether you are preparing for a procedure, studying the technique, or learning how a condition is assessed, the recording shows the process as it is performed in practice.
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