Estradiol

Pronounced es-trah-DY-ol

Brand names: Estrace, Climara, Vivelle-Dot

Type: Estrogen hormone · All Women's Health Medicines

What Estradiol is used for

  • Menopause symptoms such as hot flashes
  • Preventing bone loss after menopause (in selected patients)
  • Low estrogen states
  • Vaginal dryness and thinning (local creams and rings)

Common side effects

  • Breast tenderness
  • Headache
  • Nausea
  • Bloating
  • Breakthrough bleeding

Important cautions

  • Estrogen raises the risk of blood clots and stroke, and estrogen alone raises womb lining cancer risk — people with a uterus usually also take a progestin
  • It is generally used at the lowest effective amount with regular review, and is not started for the first time in older women to prevent chronic disease

How it comes

Tablets, skin patches, gels, sprays, vaginal creams, tablets and rings. This guide lists forms only — it never lists strengths or doses.

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Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.