Medroxyprogesterone

Pronounced me-drox-i-pro-JES-ter-one

Brand names: Provera, Depo-Provera

Type: Progestin hormone and contraceptive · All Women's Health Medicines

What Medroxyprogesterone is used for

  • Birth control (long-acting injection)
  • Protecting the womb lining during estrogen therapy
  • Treating absent or abnormal periods
  • Endometriosis pain

Common side effects

  • Irregular bleeding or stopped periods
  • Weight gain
  • Headache
  • Breast tenderness
  • Mood changes

Important cautions

  • The injection carries a boxed warning about bone density loss with long use, especially in teenagers — calcium, vitamin D, and duration are reviewed
  • Return of fertility after the last injection can be delayed for many months

How it comes

Tablets, injection (clinic). This guide lists forms only — it never lists strengths or doses.

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Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.