OrlistatOver the counter

Pronounced OR-li-stat

Brand names: Xenical, Alli

Type: Lipase inhibitor (weight loss medicine) · All Digestive (GI) Medicines

What Orlistat is used for

  • Weight management in obesity
  • Weight management in overweight patients with risk factors

◆ Kidney note

Rarely, oxalate buildup from fat malabsorption can injure the kidneys — caution in people with kidney disease or kidney stone history.

Common side effects

  • Oily or loose stools
  • Gas with discharge
  • Urgent bowel movements
  • Reduced absorption of fat-soluble vitamins

Important cautions

  • Blocks absorption of fat-soluble vitamins and some medicines such as transplant drugs — a multivitamin is usually advised at a separate time
  • Rare cases of liver and kidney injury (from oxalate) have been reported — report yellowing skin or reduced urination

How it comes

Capsules. This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Orlistat also appears on Medicines That Can Harm the Kidneys and Medicines That Can Harm the Liver.

Condition guides on MedicalVideos.com

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.