Propylthiouracil

Pronounced pro-pil-thy-o-YOOR-ah-sil

Brand names: PTU

Type: Antithyroid medicine · All Hormone & Endocrine Medicines

What Propylthiouracil is used for

  • Overactive thyroid (hyperthyroidism)
  • Graves disease, including early in pregnancy
  • Thyroid storm (hospital)

Common side effects

  • Rash
  • Nausea
  • Joint pain
  • Changes in taste

Important cautions

  • Can cause severe, sometimes fatal, liver injury — report yellowing of the skin, dark urine, or severe tiredness promptly
  • Rarely, it can sharply lower white blood cells — fever or sore throat needs urgent medical review

How it comes

Tablets. This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Propylthiouracil also appears on Medicines That Can Harm the Liver.

Related medicines — Hormone & Endocrine Medicines

Condition guides on MedicalVideos.com

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.