Pyridostigmine

Pronounced peer-id-oh-STIG-meen

Brand names: Mestinon

Type: Cholinesterase inhibitor (myasthenia medicine) · All Neurology Medicines

What Pyridostigmine is used for

  • Myasthenia gravis
  • Reversing certain anesthesia muscle blockers (hospital, related use)

◆ Kidney note

Dose is lowered in kidney disease because it is cleared by the kidneys and effects last longer.

Common side effects

  • Stomach cramps
  • Diarrhea
  • Increased saliva and tearing
  • Muscle twitching
  • Sweating

Important cautions

  • Too much causes a cholinergic crisis with severe weakness and secretions that can mimic the disease itself — new weakness needs urgent specialist review

How it comes

Tablets, extended-release tablets, liquid, injection (hospital). This guide lists forms only — it never lists strengths or doses.

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.