Valproic acid

Pronounced val-PRO-ik AS-id

Brand names: Depakene, Depakote (divalproex form)

Type: Antiseizure medicine and mood stabilizer · All Neurology Medicines

What Valproic acid is used for

• Seizure disorders (several types)
• Bipolar mania
• Migraine prevention

Common side effects

• Nausea
• Weight gain
• Tremor
• Hair loss
• Drowsiness

Important cautions

• Can cause serious birth defects and lower a child's IQ after exposure in pregnancy — it is avoided in pregnancy and used with formal precautions in girls and women who could become pregnant
• Can injure the liver and pancreas, rarely fatally, especially in young children — blood tests and symptoms are monitored
• Can raise ammonia levels and cause confusion even with normal liver tests

How it comes

Capsules, tablets, delayed and extended-release tablets, liquid, injection (hospital). This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Valproic acid also appears on Medicines That Can Harm the Liver.