Zoledronic acid

Pronounced zoe-LED-ro-nik AS-id

Brand names: Reclast, Zometa

Type: Bisphosphonate (bone medicine) · All Hormone & Endocrine Medicines

What Zoledronic acid is used for

  • Osteoporosis
  • High blood calcium from cancer
  • Bone complications of cancer
  • Paget disease of bone

◆ Kidney note

Cleared by the kidneys and can strain them — kidney function is checked before each infusion and it is avoided in severe kidney failure.

Common side effects

  • Fever and flu-like aching after infusion
  • Bone or muscle pain
  • Headache
  • Nausea

Important cautions

  • Can lower blood calcium — calcium and vitamin D levels are checked first
  • Rarely, serious jaw bone problems occur — tell your dentist you receive it

How it comes

Injection into a vein (clinic or hospital). This guide lists forms only — it never lists strengths or doses.

Toxicity lists: Zoledronic acid also appears on Medicines That Can Harm the Kidneys.

Related medicines — Hormone & Endocrine Medicines

Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.