D57.1 — Sickle-cell disease without crisis

D57.1

ICD-10 Chapter 3: Blood & Immune Disorders — illustrative image — Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89) — illustrative image

What this code means

Sickle cell disease is an inherited condition in which red blood cells become stiff and sickle-shaped, blocking small vessels.

Also called: sickle cell disease, sickle cell anemia.

When this code is used

Used for sickle cell disease without a current crisis.

Where it sits in ICD-10-CM

Code D57.1 belongs to Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism, which covers codes D50–D89 in the FY2027 ICD-10-CM tabular list. The official description above is copied verbatim from the CDC/NCHS FY2027 code file.

Related symptoms

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Frequently asked questions

What is ICD-10-CM code D57.1?

D57.1 is the ICD-10-CM diagnosis code for “Sickle-cell disease without crisis”. Sickle cell disease is an inherited condition in which red blood cells become stiff and sickle-shaped, blocking small vessels.

When is code D57.1 used?

Used for sickle cell disease without a current crisis. It belongs to Chapter 3 of ICD-10-CM (Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism).

This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.