I25.110 — Atherosclerotic heart disease of native coronary artery with unstable angina pectoris
I25.110

What this code means
Coronary artery disease with unstable angina: chest pain occurring at rest or worsening, signalling an unstable plaque.
Also called: unstable angina, atherosclerotic heart disease with unstable angina.
When this code is used
Used for atherosclerotic heart disease of a native coronary artery with unstable angina pectoris.
Where it sits in ICD-10-CM
Code I25.110 belongs to Chapter 9: Diseases of the circulatory system, which covers codes I00–I99 in the FY2027 ICD-10-CM tabular list. The official description above is copied verbatim from the CDC/NCHS FY2027 code file.
Related symptoms
Related anatomy
Frequently asked questions
What is ICD-10-CM code I25.110?
I25.110 is the ICD-10-CM diagnosis code for “Atherosclerotic heart disease of native coronary artery with unstable angina pectoris”. Coronary artery disease with unstable angina: chest pain occurring at rest or worsening, signalling an unstable plaque.
When is code I25.110 used?
Used for atherosclerotic heart disease of a native coronary artery with unstable angina pectoris. It belongs to Chapter 9 of ICD-10-CM (Diseases of the circulatory system).
This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.
More codes in Chapter 9
I10 — Essential (primary) hypertension
I11.0 — Hypertensive heart disease with heart failure
I11.9 — Hypertensive heart disease without heart failure
I12.0 — Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease
I12.9 — Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.0 — Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease