Clinical Signs Beginning With A
18 signs in this guide begin with the letter A. Every name links to a page explaining what the sign is, how it is elicited on examination, what a positive finding is associated with, and — for eponyms — who the sign is named after.
A B C D E F G H I J K L M N O P Q R S T U V W X Y
| Sign | System | A positive finding is associated with |
|---|---|---|
| Aaron's sign | Abdomen & Digestion | Described as associated with chronic appendicitis, though it is rarely used today. |
| Abadie's sign | Hormones & Metabolism | Associated with thyroid eye disease (Graves' ophthalmopathy). |
| Abdominal reflexes | Neurology | Loss of the reflexes is associated with corticospinal lesions, but also commonly with obesity, pregnancy and previous abdominal surgery. |
| Abdominojugular test | General, Eyes & Ears | Associated with right heart failure and raised right-sided filling pressures. |
| Absent red reflex | General, Eyes & Ears | Associated with congenital cataract, retinoblastoma and other serious eye conditions in childhood — it always needs prompt specialist assessment. |
| Acanthosis nigricans | Skin & Nails | Associated with insulin resistance and type 2 diabetes; rarely and when rapidly progressive in an older adult, it is associated with internal cancer. |
| Adam's forward bend test | Muscles, Bones & Joints | Associated with structural scoliosis (curvature of the spine). |
| Adson's test | Muscles, Bones & Joints | Associated with thoracic outlet compression of the subclavian artery, classically by a cervical rib or scalene muscles. |
| Allen's test | General, Eyes & Ears | Used before radial artery puncture or cannulation to check that the ulnar artery alone can supply the hand. |
| Amsler grid | General, Eyes & Ears | Associated with disease of the central retina (macula), such as age-related macular degeneration. |
| Anterior drawer test | Muscles, Bones & Joints | Associated with injury of the anterior cruciate ligament (ACL). |
| Apley's grind test | Muscles, Bones & Joints | Associated with meniscal tears of the knee. |
| Argyll Robertson pupil | Neurology | Classically associated with neurosyphilis, although other midbrain lesions can produce it. |
| Asboe-Hansen sign | Skin & Nails | Associated with blistering diseases where the skin splits easily, such as pemphigus vulgaris — an extension of the Nikolsky phenomenon. |
| Ash-leaf spots | Skin & Nails | Associated with tuberous sclerosis complex. |
| Asterixis | Abdomen & Digestion | Associated with metabolic encephalopathy, classically liver failure (hepatic encephalopathy); also seen in kidney failure and high carbon dioxide levels. |
| Auspitz's sign | Skin & Nails | Associated with psoriasis, because the thinned skin over the plaque exposes dilated capillaries. |
| Austin Flint murmur | Heart & Circulation | Associated with significant aortic regurgitation vibrating the mitral valve leaflet. |
Please note: This page is an educational reference about clinical examination signs. A clinical sign supports — and never replaces — a full clinical evaluation, examination and appropriate testing. A sign being present does not by itself prove a diagnosis, and an absent sign does not rule one out. If you have symptoms that worry you, see a health professional.