Entacapone

Pronounced en-TAK-ah-pone

Brand names: Comtan

Type: COMT inhibitor (Parkinson medicine) · All Neurology Medicines

What Entacapone is used for

• Parkinson disease, with levodopa
• Extending levodopa effect in wearing-off

Common side effects

• Diarrhea
• Orange-brown urine discoloration (harmless)
• Nausea
• Increased involuntary movements

Important cautions

• Works only together with levodopa — it has no effect on its own
• Can intensify levodopa side effects, so levodopa amounts are often adjusted

How it comes

Tablets, combination tablets with levodopa. This guide lists forms only — it never lists strengths or doses.