Rituximab

Pronounced ri-TUX-i-mab

Brand names: Rituxan

Type: Monoclonal antibody (B-cell depleting) · All Transplant & Immune Medicines

What Rituximab is used for

  • Certain lymphomas and leukemias
  • Rheumatoid arthritis
  • ANCA-associated vasculitis, including kidney involvement
  • Antibody-mediated transplant rejection and desensitization

◆ Kidney note

A key treatment for vasculitis affecting the kidneys and for antibody-mediated rejection after transplant.

Common side effects

  • Infusion reactions (fever, chills, rash)
  • Tiredness
  • Infections
  • Low white blood cell counts

Important cautions

  • Can reactivate hepatitis B, sometimes fatally — screening is done before treatment
  • Rarely linked to a serious brain infection (PML) — new neurological symptoms should be reported promptly
  • Responses to vaccines are blunted for months after treatment

How it comes

Injection into a vein (hospital or infusion clinic). This guide lists forms only — it never lists strengths or doses.

Related medicines — Transplant & Immune Medicines

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Please note: This page is a patient-education summary, not medical advice, and it deliberately contains no doses. Medicines affect everyone differently — always follow your own prescription and talk to your doctor or pharmacist before starting, stopping or changing any medicine.