C22.0 — Liver cell carcinoma

C22.0

ICD-10 Chapter 2: Neoplasms — illustrative image — Chapter 2: Neoplasms (C00–D49) — illustrative image

What this code means

Hepatocellular carcinoma is the most common type of primary liver cancer, arising from liver cells.

Also called: hepatocellular carcinoma, hcc, liver cancer.

When this code is used

Used for hepatocellular carcinoma.

Where it sits in ICD-10-CM

Code C22.0 belongs to Chapter 2: Neoplasms, which covers codes C00–D49 in the FY2027 ICD-10-CM tabular list. The official description above is copied verbatim from the CDC/NCHS FY2027 code file.

Learn more about this condition

Condition guide: Cancer

Related anatomy

Liver

Watch: related videos

▶ WatchLiver cancer treatment with radiofrequency ablation ▶ WatchDr samir abd elghaffar discussing rfa treatment of hepatocellular carcinoma ▶ WatchLiver cancer 3d animation

Frequently asked questions

What is ICD-10-CM code C22.0?

C22.0 is the ICD-10-CM diagnosis code for “Liver cell carcinoma”. Hepatocellular carcinoma is the most common type of primary liver cancer, arising from liver cells.

When is code C22.0 used?

Used for hepatocellular carcinoma. It belongs to Chapter 2 of ICD-10-CM (Neoplasms).

This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.