I21.3 — ST elevation (STEMI) myocardial infarction of unspecified site
I21.3

What this code means
An ST-elevation myocardial infarction (STEMI) is a heart attack in which a coronary artery is completely blocked.
Also called: stemi, st elevation myocardial infarction, heart attack.
When this code is used
Used for STEMI of unspecified site.
Where it sits in ICD-10-CM
Code I21.3 belongs to Chapter 9: Diseases of the circulatory system, which covers codes I00–I99 in the FY2027 ICD-10-CM tabular list. The official description above is copied verbatim from the CDC/NCHS FY2027 code file.
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Frequently asked questions
What is ICD-10-CM code I21.3?
I21.3 is the ICD-10-CM diagnosis code for “ST elevation (STEMI) myocardial infarction of unspecified site”. An ST-elevation myocardial infarction (STEMI) is a heart attack in which a coronary artery is completely blocked.
When is code I21.3 used?
Used for STEMI of unspecified site. It belongs to Chapter 9 of ICD-10-CM (Diseases of the circulatory system).
This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.
More codes in Chapter 9
I10 — Essential (primary) hypertension
I11.0 — Hypertensive heart disease with heart failure
I11.9 — Hypertensive heart disease without heart failure
I12.0 — Hypertensive chronic kidney disease with stage 5 chronic kidney disease or end stage renal disease
I12.9 — Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
I13.0 — Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease