N25.81 — Secondary hyperparathyroidism of renal origin
N25.81

What this code means
Secondary hyperparathyroidism of kidney origin: the parathyroid glands overwork because of chronic kidney disease's mineral disturbances.
Also called: secondary hyperparathyroidism, renal hyperparathyroidism, shpt.
When this code is used
Used for secondary hyperparathyroidism of renal origin.
Where it sits in ICD-10-CM
Code N25.81 belongs to Chapter 14: Diseases of the genitourinary system, which covers codes N00–N99 in the FY2027 ICD-10-CM tabular list. The official description above is copied verbatim from the CDC/NCHS FY2027 code file.
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Frequently asked questions
What is ICD-10-CM code N25.81?
N25.81 is the ICD-10-CM diagnosis code for “Secondary hyperparathyroidism of renal origin”. Secondary hyperparathyroidism of kidney origin: the parathyroid glands overwork because of chronic kidney disease's mineral disturbances.
When is code N25.81 used?
Used for secondary hyperparathyroidism of renal origin. It belongs to Chapter 14 of ICD-10-CM (Diseases of the genitourinary system).
This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.
More codes in Chapter 14
N02.8 — Recurrent and persistent hematuria with other morphologic changes
N02.B1 — Recurrent and persistent immunoglobulin A nephropathy with glomerular lesion
N04.9 — Nephrotic syndrome with unspecified morphologic changes
N05.9 — Unspecified nephritic syndrome with unspecified morphologic changes
N10 — Acute pyelonephritis
N12 — Tubulo-interstitial nephritis, not specified as acute or chronic