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Chapter 14: Diseases of the genitourinary system (N00–N99)

Kidney, bladder, prostate and genital conditions: chronic kidney disease and kidney failure, urinary infections and kidney stones, prostate enlargement, incontinence, and disorders of the male and female genital organs.

Chapter 14 spans codes N00–N99 in the FY2027 ICD-10-CM tabular list. This guide explains 63 of its most common codes — select a code for its official description, a plain-English explanation and a note on when the code is used.

ICD-10 Chapter 14: Genitourinary System — illustrative image

Codes in this chapter

CodeOfficial descriptionIn plain words
N02.8Recurrent and persistent hematuria with other morphologic changesRecurrent and persistent blood in the urine with other specified changes seen on kidney biopsy, historically used for many glomerular diseases including IgA nephropathy.
N02.B1Recurrent and persistent immunoglobulin A nephropathy with glomerular lesionPrimary IgA nephropathy is the commonest glomerular disease, in which IgA antibody deposits damage the kidney filters, often causing blood in the urine.
N04.9Nephrotic syndrome with unspecified morphologic changesNephrotic syndrome is heavy protein leakage through the kidney filters, causing low blood albumin, swelling and raised cholesterol; biopsy type unspecified.
N05.9Unspecified nephritic syndrome with unspecified morphologic changesNephritic syndrome is inflammation of the kidney filters causing blood in the urine, raised blood pressure and reduced kidney function; type unspecified.
N10Acute pyelonephritisAcute pyelonephritis is a bacterial infection of the kidney itself, causing fever, loin pain and urinary symptoms.
N12Tubulo-interstitial nephritis, not specified as acute or chronicTubulo-interstitial nephritis is inflammation of the kidney's tubules and surrounding tissue, recorded without stating whether it is acute or chronic.
N13.2Hydronephrosis with renal and ureteral calculous obstructionHydronephrosis with blockage of the kidney and ureter by a stone: urine backs up and swells the kidney because a stone obstructs the ureter.
N13.30Unspecified hydronephrosisHydronephrosis is swelling of a kidney from urine building up behind a blockage; the cause is not specified here.
N14.11Contrast-induced nephropathyContrast-induced nephropathy is kidney injury occurring after iodinated contrast dye used for scans such as CT or angiography.
N17.0Acute kidney failure with tubular necrosisAcute kidney failure with tubular necrosis: sudden kidney failure in which the kidney's tubule cells are damaged, often by low blood flow or toxins.
N17.9Acute kidney failure, unspecifiedAcute kidney failure (acute kidney injury, AKI) is a sudden fall in kidney function over hours to days; the type is not specified here.
N18.1Chronic kidney disease, stage 1Chronic kidney disease stage 1: kidney damage (such as protein in the urine) with a normal filtration rate (GFR 90 or above).
N18.2Chronic kidney disease, stage 2 (mild)Chronic kidney disease stage 2: kidney damage with a mildly reduced filtration rate (GFR 60–89).
N18.30Chronic kidney disease, stage 3 unspecifiedChronic kidney disease stage 3: a moderately reduced filtration rate (GFR 30–59), without the 3a/3b subdivision being recorded.
N18.31Chronic kidney disease, stage 3aChronic kidney disease stage 3a: a mildly-to-moderately reduced filtration rate (GFR 45–59).
N18.32Chronic kidney disease, stage 3bChronic kidney disease stage 3b: a moderately-to-severely reduced filtration rate (GFR 30–44).
N18.4Chronic kidney disease, stage 4 (severe)Chronic kidney disease stage 4: a severely reduced filtration rate (GFR 15–29), one stage before kidney failure.
N18.5Chronic kidney disease, stage 5Chronic kidney disease stage 5: a filtration rate below 15, the most advanced stage before or approaching kidney failure.
N18.6End stage renal diseaseEnd-stage renal disease (ESRD) is kidney failure requiring dialysis or transplantation to sustain life.
N18.9Chronic kidney disease, unspecifiedChronic kidney disease (CKD) is long-term loss of kidney function; the stage is not specified here.
N19Unspecified kidney failureKidney failure recorded without stating whether it is acute or chronic.
N20.0Calculus of kidneyA kidney stone (calculus) is a hard deposit of minerals that forms in the kidney and can cause severe loin pain if it moves.
N20.1Calculus of ureterA stone (calculus) lodged in the ureter, the tube carrying urine from kidney to bladder, typically causing renal colic.
N20.9Urinary calculus, unspecifiedA urinary calculus (stone) somewhere in the urinary tract; the exact site is not specified.
N23Unspecified renal colicRenal colic is severe, wave-like loin-to-groin pain, usually from a stone moving down the ureter; cause unspecified here.
N25.0Renal osteodystrophyRenal osteodystrophy is bone disease caused by the mineral and hormone disturbances of chronic kidney disease.
N25.1Nephrogenic diabetes insipidusNephrogenic diabetes insipidus is inability of the kidneys to respond to the water-saving hormone ADH, causing large volumes of dilute urine.
N25.81Secondary hyperparathyroidism of renal originSecondary hyperparathyroidism of kidney origin: the parathyroid glands overwork because of chronic kidney disease's mineral disturbances.
N28.1Cyst of kidney, acquiredAn acquired cyst of the kidney is a fluid-filled sac in the kidney, usually a simple cyst found on a scan.
N28.9Disorder of kidney and ureter, unspecifiedA disorder of the kidney or ureter recorded without further detail.
N30.00Acute cystitis without hematuriaAcute cystitis is a sudden bladder infection causing burning on urination and urgency, here without blood in the urine.
N30.01Acute cystitis with hematuriaAcute cystitis (bladder infection) in which blood is visible in the urine.
N30.90Cystitis, unspecified without hematuriaCystitis is inflammation of the bladder, usually from infection; here without blood in the urine and without acuity stated.
N32.81Overactive bladderOveractive bladder is a pattern of urgency to urinate, usually with frequency and night-time urination, sometimes with leakage.
N39.0Urinary tract infection, site not specifiedA urinary tract infection (UTI) is a bacterial infection of the urinary system; the exact site is not specified here.
N39.3Stress incontinence (female) (male)Stress incontinence is leakage of urine when pressure rises in the abdomen, such as coughing, sneezing or exercise.
N39.41Urge incontinenceUrge incontinence is leakage of urine that follows a sudden, hard-to-defer need to urinate.
N39.46Mixed incontinenceMixed incontinence is urinary leakage with features of both stress and urge incontinence.
N40.0Benign prostatic hyperplasia without lower urinary tract symptomsAn enlarged prostate (benign prostatic enlargement) without lower urinary tract symptoms being recorded.
N40.1Benign prostatic hyperplasia with lower urinary tract symptomsAn enlarged prostate causing lower urinary tract symptoms such as slow stream, hesitancy, frequency and night-time urination.
N41.0Acute prostatitisAcute prostatitis is a sudden bacterial infection and inflammation of the prostate gland, causing fever and urinary pain.
N41.9Inflammatory disease of prostate, unspecifiedInflammatory disease of the prostate (prostatitis) recorded without stating whether it is acute or chronic.
N45.1EpididymitisEpididymitis is inflammation of the epididymis, the coiled tube behind the testicle, causing scrotal pain and swelling.
N47.1PhimosisPhimosis is a tight foreskin that cannot be pulled back over the head of the penis.
N48.1BalanitisBalanitis is inflammation of the head of the penis, causing soreness, redness and sometimes discharge.
N50.819Testicular pain, unspecifiedPain in the testicle, recorded as a finding without the side or cause being specified.
N52.9Male erectile dysfunction, unspecifiedErectile dysfunction is difficulty getting or keeping an erection firm enough for sex; cause not specified here.
N61.0Mastitis without abscessMastitis is inflammation of breast tissue, usually with infection during breastfeeding; here without an abscess.
N63.0Unspecified lump in unspecified breastA lump in the breast whose side and position are not specified; most breast lumps are benign but need assessment.
N64.4MastodyniaMastodynia is pain in the breast, which is commonly hormonal and cyclical.
N73.9Female pelvic inflammatory disease, unspecifiedPelvic inflammatory disease (PID) is infection of the uterus, fallopian tubes or ovaries, usually sexually transmitted.
N76.0Acute vaginitisAcute vaginitis is sudden inflammation of the vagina, usually from infection such as thrush or bacterial vaginosis.
N80.9Endometriosis, unspecifiedEndometriosis is a condition in which tissue like the womb lining grows outside the uterus, causing pain and sometimes infertility.
N81.4Uterovaginal prolapse, unspecifiedUterovaginal prolapse is descent of the uterus and vaginal walls from their normal position; degree not specified.
N83.209Unspecified ovarian cyst, unspecified sideAn ovarian cyst is a fluid-filled sac on an ovary; side and type not specified. Most are benign and resolve on their own.
N91.2Amenorrhea, unspecifiedAmenorrhoea is the absence of menstrual periods; whether primary or secondary is not specified here.
N92.0Excessive and frequent menstruation with regular cycleExcessive and frequent menstruation with a regular cycle: periods that are heavy, frequent, or both, coming regularly (menorrhagia).
N92.6Irregular menstruation, unspecifiedIrregular menstruation means periods that vary unpredictably in timing or flow; pattern not specified here.
N93.9Abnormal uterine and vaginal bleeding, unspecifiedAbnormal bleeding from the uterus or vagina that does not fit a normal period pattern; cause not specified.
N94.6Dysmenorrhea, unspecifiedDysmenorrhoea is painful periods, with cramping lower abdominal pain around menstruation; type not specified.
N95.0Postmenopausal bleedingPostmenopausal bleeding is any vaginal bleeding occurring after the menopause and always needs assessment.
N95.1Menopausal and female climacteric statesMenopausal and female climacteric states cover the symptoms of the menopause transition, such as hot flushes and night sweats.
N97.9Female infertility, unspecifiedFemale infertility is difficulty conceiving after a period of trying; the cause is not specified here.

This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.

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