- Physical Examination
- Surgical Examination
- Ophthalmology
- Clinical Skills
- Orthopedics
- Surgery Videos
- Laparoscopy
- Pediatrics
- Funny Videos
- Cardiothoracic Surgery
- Nursing Videos
- Plastic Surgery
- Otorhinolaryngology
- Histology and Histopathology
- Neurosurgery
- Dermatology
- Pediatric Surgery
- Urology
- Dentistry
- Oncology and Cancers
- Anatomy Videos
- Health and Fitness
- Radiology
- Anaesthesia
- Physical Therapy
- Pharmacology
- Interventional Radiology
- Cardiology
- Endocrinology
- Gynecology
- Emergency Medicine
- Psychiatry and Psychology
- Childbirth Videos
- General Medical Videos
- Nephrology
- Physiology
- Diet and Food Health
- Diabetes Mellitus
- Neurology
- Women Health
- Osteoporosis
- Gastroenterology
- Pulmonology
- Hematology
- Rheumatology
- Toxicology
- Nuclear Medicine
- Infectious Diseases
- Vascular Disease
- Reproductive Health
- Burns and Wound Healing
- Kidney Zone Podcast
- Other
D68.51 — Activated protein C resistance
D68.51
What this code means
Activated protein C resistance, usually due to the factor V Leiden variant, makes blood more likely to clot.
Also called: factor v leiden, activated protein c resistance.
When this code is used
Used for activated protein C resistance.
Where it sits in ICD-10-CM
Code D68.51 belongs to Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism, which covers codes D50–D89 in the FY2027 ICD-10-CM tabular list. The official description above is copied verbatim from the CDC/NCHS FY2027 code file.
Related symptoms
Frequently asked questions
What is ICD-10-CM code D68.51?
D68.51 is the ICD-10-CM diagnosis code for “Activated protein C resistance”. Activated protein C resistance, usually due to the factor V Leiden variant, makes blood more likely to clot.
When is code D68.51 used?
Used for activated protein C resistance. It belongs to Chapter 3 of ICD-10-CM (Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism).
This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.