Chapter 22: Codes for special purposes (U00–U85)
Codes reserved for urgent public-health use and provisional assignment of new diseases. At present this chapter carries the codes for COVID-19, post-COVID condition and vaping-related disorder.
Chapter 22 spans codes U00–U85 in the FY2027 ICD-10-CM tabular list. This guide explains 3 of its most common codes — select a code for its official description, a plain-English explanation and a note on when the code is used.

Codes in this chapter
| Code | Official description | In plain words |
|---|---|---|
| U07.0 | Vaping-related disorder | A vaping-related disorder is lung injury or another disorder linked to vaping (e-cigarette use), including EVALI-type lung injury. |
| U07.1 | COVID-19 | COVID-19 is the illness caused by the SARS-CoV-2 virus, ranging from mild respiratory illness to severe pneumonia. |
| U09.9 | Post COVID-19 condition, unspecified | Post COVID-19 condition ('long COVID') covers symptoms that continue or develop after a COVID-19 infection, such as fatigue and breathlessness. |
This guide explains ICD-10-CM codes in plain language for patients, students and other readers. It is educational information only — not coding, billing or medical advice. The code recorded for any real encounter is assigned from the full clinical documentation by the treating team and qualified coders, and only they can decide which code fits a specific case.
Other chapters
- Chapter 1: Infectious & Parasitic Diseases
- Chapter 2: Neoplasms
- Chapter 3: Blood & Immune Disorders
- Chapter 4: Endocrine, Nutritional & Metabolic
- Chapter 5: Mental, Behavioral & Neurodevelopmental
- Chapter 6: Nervous System
- Chapter 7: Eye & Adnexa
- Chapter 8: Ear & Mastoid Process
- Chapter 9: Circulatory System
- Chapter 10: Respiratory System
- Chapter 11: Digestive System
- Chapter 12: Skin & Subcutaneous Tissue
- Chapter 13: Musculoskeletal & Connective Tissue
- Chapter 14: Genitourinary System
- Chapter 15: Pregnancy, Childbirth & Puerperium
- Chapter 16: Perinatal Period
- Chapter 17: Congenital & Genetic Disorders
- Chapter 18: Symptoms, Signs & Abnormal Findings
- Chapter 19: Injury & Poisoning
- Chapter 20: External Causes of Morbidity
- Chapter 21: Factors Influencing Health Status